Download M.Sc. Chemistry "Chemistry of Natural Products" Question Paper-3 of 4th Semester M.Sc. Chemistry, Download All Previous Years Question Papers.

M.Sc. Chemistry 4th Semester
Chemistry of Natural Products
Paper-III

Time Allowed: Three Hours] [Maximum Marks: 80

Note: Attempt five questions in all, selecting at least one question from each Unit. Question No. 9 is compulsory.

UNIT-I

1. 

(a) Establish the struc uree plytol.

(b) How will you synthes the B care facem acetylene and ceraldehyde? 

2. (a) Briefly discuss the general metho is of structure denomination of terpenoids

(b) Outline the syr thesis of a-Terpreol from P-jodopropionic acid or P-toluic acid.

UNIT-II

3. (a) Briefly discuss the following methods of structure determination of alkaloids: 

(i) Hofmann degradation

(ii) Emde degradation 

(iii) Van Brauri's method of degradation.

(b) Describe the various steps involved in the synthesis of quinine.

4. (a) Discuss the Robinson synthesis of Tropine. How will you convert Tropine to Atropine?

 (b) Discuss the physiological action of alkaloids and describe the biosynthesis of nicotine.

UNIT-III

5. (a) Give adequate chemical evidences to establish the following:

(i) Angular methyl groups in cholesterol.

(ii) Nature, length, and position of side chain in cholesterol.

(b) What type of steroid is testosterone? Discuss the synthesis of testosterone from cholesterol.

6. (a) Establish the position of the keto group and angular methyl group in estrone.

 (b) Discuss briefly the biosynthesis of steroids.

UNIT-IV 

7. (a) How structure of cyanine chloride was established?

(b) Explain the shikimic acid pathway for biosynthesis of plant pigments.

8. (a) Write the synthesis of prostaglandin PGF, from cyclopentadiene.

(b) Draw the neat structural formula of the following:

(i) Chlorophyll 

(ii) Hemoglobin

(iii) Ryrethrin I and II.

UNIT-V

9. (a) What is Diel's Hydrocarbon? Write the synthesis of Diel's Hydrocarbon from 2, 5-dimethyl cyclopentanone.

(b) How can morphine be isolated from natural sources?

c) Discuss the mechanism of formation of mevalonic acid from acetyl-coenzyme.

(d) How will you estimate the number of -OCH3’ -OH and –NCH3 groups in natural products? Give the name of these methods.